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Researcher at Research Department
Ask questions about Saleh Alkarim's research, publications, and ongoing work
Investigated the impact of exosomes derived from cancer stem cells and mesenchymal stem cells (MSCs) on the progression of diethylnitrosamine (DEN)-induced hepatocellular carcinoma (HCC) in rats, providing insights into potential therapeutic targets.
Focused on identifying and targeting signal transduction pathways within cancer stem cells to develop therapeutic strategies against cancer metastasis, a critical step in improving cancer treatment.
Demonstrated that Anethum graveolens (dill) induces apoptosis and cell cycle arrest in the HepG2 cell line, suggesting its potential as a natural anti-cancer agent.
Explored the therapeutic potential of stem cell-based therapies for treating neurological disorders, highlighting the promise of this approach in regenerative medicine.
Showed that ellagic acid modulates the amyloid precursor protein (APP) gene via superoxide dismutase regulation in an experimental Alzheimer's model, suggesting a potential therapeutic role.
Investigated the effects of maternal age on the expression of mesenchymal stem cell markers in human umbilical cord components, contributing to the understanding of stem cell properties.
Identified novel natural molecular candidates for treating human neuroblastoma using pharmacophore-model-based virtual screening approaches, advancing drug discovery efforts.
Dr. Saleh Alkarim is a leading researcher in cancer stem cell biology and regenerative medicine, with significant contributions to understanding the therapeutic potential of stem cells and natural compounds in treating cancer and neurological disorders. His work focuses on innovative approaches to target cancer metastasis and promote tissue repair.
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