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Sami A. Al‐Hussain
Assistant professor at Chemistry
Drug Discovery
Multicomponent Synthesis Of Heterocycles
Synthesis And Biological Activity
Synthesis And Biological Evaluation
Synthesis And Characterization Of Heterocyclic Compounds
1.9K
Citations
23
H-index
0
Patents
100
Publications
0
Grants
$0
Total Funding
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Research Contributions
Development of VEGFR-2 inhibitors for anti-renal cancer activity
Designed and synthesized novel indolyl-1,2,4-triazole hybrids that exhibited potent VEGFR-2 inhibitory activity, demonstrating potential for anti-renal cancer treatment.
Bioorganic Chemistry (2020)
Synthesis of novel pyrazole derivatives with potential antimicrobial and anticancer properties
Synthesized novel pyrazole derivatives incorporating oxa/thiadiazolyl, pyrazolyl moieties, and pyrazolo[4,3-d]-pyrimidine derivatives, demonstrating potential as antimicrobial and anticancer agents.
Bioorganic & Medicinal Chemistry Letters (2016)
Investigation of novel benzodifuranyl, triazine, and thiazolopyrimidine derivatives as anti-inflammatory and analgesic agents
Synthesized novel benzodifuranyl, 1,3,5-triazines, 1,3,5-oxadiazepines, and thiazolopyrimidine derivatives derived from visnaginone and khellinone, showing potential as anti-inflammatory and analgesic agents.
Molecules (2020)
Discovery of novel compounds as SARS-CoV-2 inhibitors using QSAR and molecular docking
Utilized QSAR-based virtual screening, molecular docking, and molecular dynamics simulations to identify novel compounds with potential as SARS-CoV-2 inhibitors.
Pharmaceuticals (2021)
Development of new 1,2,4-triazole/1,3,4-thiadiazole derivatives as anticancer agents
Designed and synthesized new 1,2,4-triazole/1,3,4-thiadiazole derivatives with spiroindoline, imidazo[4,5-b]quinoxaline and thieno[2,3-d]pyrimidine from isatin derivatives, showing promising anticancer activity.
Molecules (2022)
Synthesis of novel bis-thiazole derivatives and their antimicrobial profile
Synthesized new bis-thiazole derivatives and investigated their antimicrobial activity, including in silico simulation studies.
Arabian Journal of Chemistry (2021)
Development of novel benzofuran-1,3,4-oxadiazoles as lead inhibitors of M. tuberculosis
Designed and synthesized novel benzofuran-1,3,4-oxadiazoles as lead inhibitors of M. tuberculosis polyketide synthase 13.
Pharmaceuticals (2023)
Research Highlights
Dr. Sami A. Al-Hussain is an expert in the synthesis and biological evaluation of heterocyclic compounds, with a focus on drug discovery and the application of computational methods. His research has significantly contributed to the development of novel anticancer and antimicrobial agents.
Research Areas
Drug DiscoveryMulticomponent Synthesis Of HeterocyclesSynthesis And Biological ActivitySynthesis And Biological EvaluationSynthesis And Characterization Of Heterocyclic Compounds
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