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Professor at Pharmaceutical Chemistry Department
Ask questions about Sara T. Al‐Rashood's research, publications, and ongoing work
Designed and synthesized novel N-substituted isatins-SLC-0111 hybrids as carbonic anhydrase inhibitors and antitumor agents, enhancing hydrophobic interactions within the active site.
Developed isatin-thiazolo[3,2-a]benzimidazole hybrids as novel CDK2 inhibitors with potent in vitro apoptotic anti-proliferative activity, supported by molecular dynamics investigations.
Investigated the antitumor properties of certain spirooxindoles towards hepatocellular carcinoma, demonstrating antioxidant activity.
Synthesized and evaluated the in vitro anticancer activity of novel 1-(2-methyl-6-arylpyridin-3-yl)-3-phenylureas as apoptosis-inducing agents.
Designed and synthesized 6-arylpyridine-tethered sulfonamides as novel selective inhibitors of carbonic anhydrase IX with promising antitumor features towards the human colorectal cancer.
Designed and synthesized novel oxindole/benzofuran hybrids as potential dual CDK2/GSK-3β inhibitors targeting breast cancer, with biological evaluation and in silico studies.
Identified potential SARS-CoV-2 2'-O-methyltransferase (nsp16) inhibitors through structure-based virtual screening, molecular dynamics simulation, and MM-PBSA approaches.
Professor Sara T. Al-Rashood is a leading pharmaceutical chemist specializing in drug discovery and design, with a focus on developing novel cancer therapeutics and inhibitors. Her research has significantly contributed to the understanding of enzyme inhibition and the development of innovative drug candidates.
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