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Professor (and Principal Investigator) at Center of Excellence in Genomic Medicine Research, King Fahd Medical Research Center at KAU
Ask questions about Shazi Shakil's research, publications, and ongoing work
Characterized the types, epidemiology, and treatment strategies for antibiotic resistance, particularly focusing on extended-spectrum beta-lactamases (ESBLs).
Evaluated the antimicrobial potential of five herbal extracts against multi-drug resistant bacteria and fungi of clinical origin, highlighting natural alternatives to conventional antibiotics.
Reviewed the application of nanotechnology in cancer therapy, including drug delivery, imaging, and diagnostics, emphasizing the potential of nanoparticles in targeted cancer treatment.
Created a user-friendly, step-by-step guide for performing molecular docking simulations using AutoDock 4.2, making it accessible to researchers without extensive bioinformatics expertise.
Investigated the link between protein misfolding and aggregation in the pathogenesis of Alzheimer's disease and Type 2 Diabetes Mellitus, exploring potential therapeutic targets.
Identified a novel compound from Trachyspermum ammi (Ajowan caraway) seeds exhibiting antibiofilm and antiadherence activities against Streptococcus mutans, suggesting its potential as a chemotherapeutic agent against dental caries.
Explored the therapeutic potential of anti-diabetic drugs in the treatment of Alzheimer's disease, focusing on their ability to inhibit acetylcholinesterase and other relevant targets.
Synthesized and characterized cefotaxime-conjugated gold nanoparticles and evaluated their efficacy in targeting drug-resistant CTX-M-producing bacterial pathogens, demonstrating a novel approach to combat antibiotic resistance.
Dr. Shazi Shakil is a leading expert in drug discovery and antibiotic resistance, utilizing computational methods and nanotechnology to combat infectious diseases and neurological disorders. His research focuses on enzyme-ligand interactions and the development of novel therapeutic strategies.
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