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Researcher at Research Department
Ask questions about Sumit O. Bajaj's research, publications, and ongoing work
Developed a de novo asymmetric synthesis of the mezzettiaside family of natural products using a dual B-/Pd-catalyzed glycosylation approach, demonstrating a novel method for complex carbohydrate construction.
Synthesized and evaluated digitoxin analogs, identifying compounds with enhanced anticytomegalovirus activity, contributing to the development of potential antiviral therapeutics.
Provided a perspective on the total synthesis of thapsigargin, a promising anticancer drug, highlighting synthetic challenges and potential solutions.
Identified potential anti-SARS-CoV-2 compounds from food sources using QSAR-based virtual screening, molecular docking, and molecular dynamics simulation analysis, offering insights into dietary interventions.
Investigated the structure-activity relationship of mezzettiasides and their disaccharide analogs, revealing insights into their anticancer and antibacterial activities.
Developed a method for synthesizing modular building blocks using glycosyl phosphate donors, enabling the construction of asymmetric N-glycans.
Sumit O. Bajaj specializes in the synthesis of complex carbohydrates and their application in drug discovery, with a focus on developing novel therapeutic agents and understanding structure-activity relationships of natural products. His research encompasses asymmetric synthesis, glycosylation methodologies, and the identification of anti-viral and anti-cancer compounds.
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