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Researcher at Research Department
Ask questions about Tlili Barhoumi's research, publications, and ongoing work
Demonstrated the protective role of T regulatory lymphocytes in preventing angiotensin II-induced hypertension and vascular injury, a key finding in understanding the immune system's role in cardiovascular disease.
Showed that endothelin-1 overexpression exacerbates atherosclerosis and induces aortic aneurysms in apolipoprotein E knockout mice, highlighting the role of endothelin-1 in vascular disease.
Identified the role of gamma/delta T cells in mediating angiotensin II-induced hypertension and vascular injury, providing insights into the cellular mechanisms of hypertension.
Investigated the effects of the SARS-CoV-2 spike protein on THP-1-like macrophages, including apoptosis, inflammation, and oxidative stress, and explored the potential of angiotensin-converting enzyme inhibitors.
Demonstrated that the knockdown of miR-431-5p protects against angiotensin II-induced hypertension and vascular injury, suggesting a potential therapeutic target.
Investigated the role of monocytes/macrophages in renin-angiotensin system-induced hypertension and end organ damage, contributing to the understanding of the disease.
Dr. Tlili Barhoumi is a leading researcher in cardiovascular disease, hypertension, and the role of immune cells. His work focuses on the mechanisms of vascular injury and the impact of inflammation and oxidative stress, with recent contributions to COVID-19 research.
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