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Vikneswaran Murugaiyah
Researcher at Research Department
Alkaloids: Synthesis And Pharmacology
Chemical Synthesis And Alkaloids
Cholinesterase And Neurodegenerative Diseases
Drug Discovery
Traditional And Medicinal Uses Of Annonaceae
3.8K
Citations
38
H-index
0
Patents
99
Publications
0
Grants
$0
Total Funding
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Research Contributions
Discovery of Novel Spirooxindole-Hexahydropyrrolizines as Cholinesterase Inhibitors
Synthesized and identified novel piperidone-grafted mono- and bis-spirooxindole-hexahydropyrrolizines demonstrating potent cholinesterase inhibitory activity, offering potential therapeutic avenues for neurodegenerative diseases.
Bioorganic & Medicinal Chemistry (2013)
Elucidation of Antihyperuricemic Mechanisms of Phyllanthus niruri
Investigated the mechanisms underlying the antihyperuricemic effect of Phyllanthus niruri and its lignan constituents, providing insights into its traditional use for treating gout and related conditions.
Journal of Ethnopharmacology (2009)
Development of Lyophilized Hybrid Nanostructured Lipid Carriers for Enhanced Drug Delivery
Developed and optimized lyophilized hybrid nanostructured lipid carriers to enhance the cellular uptake of verapamil, improving its bioavailability and therapeutic efficacy.
Nanoscale Research Letters (2018)
Identification of Prenylated Xanthones from Mangosteen as Cholinesterase Inhibitors
Identified prenylated xanthones from mangosteen as promising cholinesterase inhibitors and conducted molecular docking studies to understand their mechanism of action, highlighting their potential for Alzheimer's disease treatment.
Phytomedicine (2014)
Pharmacokinetic Study of Mitragynine from Kratom
Developed a method for determining mitragynine in plasma and applied it to a pharmacokinetic study in rats, contributing to the understanding of kratom's analgesic effects.
Analytical and Bioanalytical Chemistry (2010)
Evaluation of Anticancer Attributes of Illicium verum Essential Oils
Demonstrated the anticancer attributes of Illicium verum (star anise) essential oils against colon cancer cells, suggesting its potential as a natural anticancer agent.
South African Journal of Botany (2015)
Investigation of Hypoglycemic Effects of Gynura procumbens
Studied the hypoglycemic and anti-hyperglycemic effects of Gynura procumbens leaf extracts in diabetic rats, supporting its traditional use for managing diabetes.
Asian Pacific Journal of Tropical Biomedicine (2013)
Development of HPLC Method for Lignan Determination in Phyllanthus niruri
Developed a simple HPLC method with fluorescence detection for determining four lignans in Phyllanthus niruri, enabling pharmacokinetic studies and quality control of herbal products.
Journal of Chromatography A (2007)
Research Highlights
Vikneswaran Murugaiyah is a leading researcher in pharmaceutical sciences, focusing on drug discovery, cholinesterase inhibitors, and ethnopharmacology. His work explores natural products and synthetic compounds for therapeutic applications, with a strong emphasis on neurodegenerative diseases and metabolic disorders.
Research Areas
Alkaloids: Synthesis And PharmacologyChemical Synthesis And AlkaloidsCholinesterase And Neurodegenerative DiseasesDrug DiscoveryTraditional And Medicinal Uses Of Annonaceae
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