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Zhuorong Li
Researcher at Research Department
Bone Metabolism And Diseases
Hepatitis B Virus Studies
Hepatitis C Virus Research
Synthesis And Biological Activity
Synthesis And Biological Evaluation
4.9K
Citations
35
H-index
0
Patents
100
Publications
0
Grants
$0
Total Funding
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Research Contributions
Identified Berberine as a Novel Cholesterol-Lowering Drug
Discovered that berberine, a natural compound, lowers cholesterol through a unique mechanism distinct from statins, offering a new approach to treating hyperlipidemia.
Nature Medicine (2004)
Demonstrated Berberine's Insulin-Sensitizing Effects
Showed that berberine reduces insulin resistance by upregulating insulin receptor expression via protein kinase C, providing insights into diabetes treatment.
Metabolism (2008)
Developed Small Molecular Compounds to Inhibit HIV-1 Replication
Identified small molecules that specifically stabilize APOBEC3G, a host protein, to inhibit HIV-1 replication, offering a potential antiviral strategy.
Journal of Biological Chemistry (2010)
Synthesized and Evaluated Carbazole Sulfonamides as Antimitotic Agents
Synthesized a novel class of carbazole sulfonamides and demonstrated their potential as antimitotic agents against solid tumors, contributing to cancer drug development.
Journal of Medicinal Chemistry (2006)
Investigated the Role of MicroRNA-200a-3p in Neuroprotection
Showed that microRNA-200a-3p mediates neuroprotection in Alzheimer's disease by coregulating BACE1 and PRKACB, offering a potential therapeutic target.
Frontiers in Pharmacology (2019)
Explored the Antiviral Potential of Formononetin
Demonstrated that formononetin inhibits enterovirus 71 replication by regulating COX-2/PGE2 expression, providing a potential treatment for EV71 infections.
Virology Journal (2015)
Synthesized and Evaluated Novel Benzimidazole Derivatives
Designed and synthesized novel benzimidazole derivatives and evaluated their anti-tumor activity, contributing to the development of new cancer therapeutics.
European Journal of Medicinal Chemistry (2016)
Research Highlights
Professor Zhuorong Li is a leading researcher in medicinal chemistry, focusing on the discovery and development of novel therapeutics for various diseases, including cancer, viral infections, and metabolic disorders. His work has significantly contributed to understanding drug mechanisms and identifying potential drug targets.
Research Areas
Bone Metabolism And DiseasesHepatitis B Virus StudiesHepatitis C Virus ResearchSynthesis And Biological ActivitySynthesis And Biological Evaluation
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